AN UNBIASED VIEW OF PT2399

mitotane will decrease the extent or impact of abemaciclib by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Steer clear of or Use Alternate Drug. Coadministration of abemaciclib with powerful CYP3A4 inducers minimizes plasma concentration of abemaciclib and its metabolites.duvelisib will enhance the degree or effect of abemaciclib by affec